Spastic paraplegia 4 (SPG4; generally known as SPAST-HSP) is characterised by insidiously progressive bilateral decrease-limb gait spasticity. Over fifty% of impacted persons have some weakness from the legs and impaired vibration sense for the ankles.?? ????? ???? ??? ???? ?? ??? ? ?? ???? ??? ? ????. ?? ????? ??? ????? ??? ???? ?? ???? ??????!???